Publications

“CRISPR Screening in Tandem with Targeted mtDNA Damage Reveals WRNIP1 Essentiality.”

T. Sack, P. Dhavarasa, D. Szames, S. O’Brien, S. Angers and S. O. Kelley.
ACS Chem. Biol., 2023, 18(12): 2599-2609.

“Identification of Druggable Regulators of Cell Secretion Via a Kinome-Wide Screen and High-Throughput Immunomagnetic Cell Sorting.”

M. Labib, Z. Wang, Y. Kim, S. Lin, A. Abdrabou, H. Yousefi, P. Lo, S. Angers. E.H. Sargent, and S.O. Kelley.
Nature Biomedical Engineering, 2023,10.1038/s41551-023-01135.

“Apta FastZ: An Algorithm for the Rapid Identification of Aptamers with Defined Binding Affinities.”

Z. Wang, D. Chang, E.H. Sargent, and S.O. Kelley.
Anal. Chem. 2023. 95(48): 17438-17443.

“Self-Assembled Homopolymeric Spherulites from Small Molecules in Solution.”

Q. Song, Y. Li, Z. Jin, H. Liu, M.N. Creyer, W. Yim, Y. Huang, X. Hu, T. He, Y. Li, S.O. Kelley, L. Shi, J. Zhou, and J.V. Jokerst.
Journal of the American Chemical Society, 2023. 145(47): 25664-25672.

“A Magneto-Activated Nanoscale Cytometry Platform for Molecular Profiling of Small Extracellular Vesicles.”

K. Chen, B. Duong, S. Ahmed, P. Dhavarasa, Z. Wang, M. Labib, C. Flynn, J. Xu, Y. Zhang, H. Wang, X. Yang, J. Das, H. Zargartalebi, Y. Ma, and S. O. Kelley.
Nature Communications, 2023, Volume 14, 5576.

“Isolation of Tumour-Reactive Lymphocytes from Peripheral Blood Via Microfluidic Immunomagnetic Cell Sorting.”

Z. Wang, S. Ahmed, M. Labib, H. Wang, L. Wu, F. Bavaghar-Zaeimi, N. Shokri, S. Blanco, S. Karim, K. Czarnecka-Kujawa, E.H. Sargent, and S.O. Kelley.
Nature Biomedical Engineering, 2023. 7, 1188–1203

“Biomolecular Sensors for Advanced Physiological Monitoring.”

C.D. Flynn, D. Chang, A. Mahmud, H. Yousefi, J. Das, K. Riordan, E. Sargent, and S. O. Kelley.
Nature Reviews Bioengineering 2023.  1(8): 560-575.

“A High-Dimensional Microfluidic Approach for Selection of Aptamers with Programmable Binding Affinities.”

D. Chang, Z. Wang, C. Flynn, A. Mahmud, M. Labib, H. Wang, A. Geraili, X. Li, J. Zhang, E. Sargent, and S. O. Kelley.
Nature Chemistry, 2023, 15(6), 773–780.

“Monitoring Cardiac Biomarkers with Aptamer-Based Molecular Pendulum Sensors.”

A. Mahmud, D. Chang, J. Das, S. Gomis, F. Foroutan, J. Chen, L. Pandey, C. Flynn, H. Yousefi, A. Geraili, H. Ross, E.H. Sargent, and S.O. Kelley.
Angewandte Chemie, 2023. 135(2), e202213567.

“Abstract B014: Phenotypic CRISPR Genome-Wide Screening for the Discovery of Genetic Regulators of Allele-Specific Mutant KRAS”

X. Hu, R. Singh, and S.O. Kelley.
Molecular Cancer Research, 2023. 21(5_Supplement), B014.

“Highly Stable Bio-Templated InP/ZnSe/ZnS Quantum Dots for Specific Monitoring of Bacterial Membrane Proteins.”

H. Yousefi, L. Sagar, A. Geraili, D. Chang, F. Pelayo Garcia de Arguer, C.D. Flynn, S. Lee, E. Sargent, and S. O. Kelley.

Chem Rxiv 2023.

“Efficient Delivery of Biological Cargos into Primary Cells by Electrodeposited Nanoneedles via Cell-Cycle-Dependent Endocytosis”

Z. Wang, H. Wang, S. Lin, M. Labib, S. Ahmed, J. Das, S. Angers, E.H. Sargent, and S.O. Kelley.
Nano Letters, 2023. (13), 5877-5885.

“CRISPR-Induced DNA Reorganization for Multiplexed Nucleic Acid Detection“

M. Karlikow, E. Amalfitano, X. Yang, J. Doucet, A. Chapman, P.S. Mousavi, P. Homme, P. Sutyrina, W. Chan, S. Lemak, A. Yakunin, A. Dolezal, S.O. Kelley, L. Foster, B. Harpur, and K. Pardee.
Nature Communications 2023. (14), 1505.

“Digital Microfluidics as an Emerging Tool for Bacterial Protocals”

C.R. Nemr, A.A. Sklavounos, A.R. Wheeler, and S.O. Kelley.
SLAS Technology, 2023. 28(1), 2-15.

“Capillary-Assisted Molecular Pendulum Bioanalysis”

H. Zargartalebi, H. Yousefi, C.D. Flynn, S. Gomis, J. Das, T.L. Young, E. Chien, S. Mubareka, A. McGeer, H. Wang, E.H. Sargent, A.S. Nezhad, and S.O. Kelley.
J. Am. Chem. Soc., 2022, 40, 18338-18349.

“Genome-wide in Vivo Screen of Circulating Tumor Cells Identifies SLIT2 as a Regulator of Metastasis.”

F. Xia, Y. Ma, K. Chen, B. Duong, S. Ahmed, R. Atwal, D. Philpott, T. Ketela, J. Pantea, S. Lin, S. Angers, S. O. Kelley
Science Advances, 2022, 35, eabo7792.

“Nanoparticle Amplification Labeling for High-Performance Magnetic Cell Sorting”

Z. Wang, H. Wang, S. Lin, S. Ahmed, S. Angers, E. H. Sargent, S.O. Kelley
Nano Letters, 2022, 12, 4774-4783.

“Efficient Recovery of Potent Tumor-Infiltrating Lymphocytes Through Quantitative Immunomagnetic Cell Sorting.”

Z. Wang, S. Ahmed, M. Labib, H. Wang, X. Hu, J. Wei, Y. Yao, J. Moffat, E.H. Sargent, S.O. Kelley.
Nature Biomedical Engineering, 2022, 6, 108-117.

“Rapid On-Cell Selection of High-Performance Human Antibodies.”

D. N. Philpott, S. Gomis, H. Wang, R. Atwal, A. Kelil, T. Sack, B. Morningstar, C. Burnie, E.H. Sargent, S. Angers, S.S. Sidhu, S.O. Kelley.
ACS Central Science, 2022, 8, 102-109.

“Ultrathroughput Immunomagnetic Cell Sorting Platform”

D. N. Philpott, K. Chen, R. Atwal, D. Li, J. Christie, E.H. Sargent, S.O. Kelley.
Lab Chip, 2022, 22(24):4822-4830.

“Challenges and Opportunities for Wearable Sensing Systems.”

S.O. Kelley.
ACS Sensors, 2022, 7, 345-346.

“PillarX: A Microfluidic Device to Profile Circulating Tumor Cell Clustors Based on Geometry, Deformability, and Epithelial State.”

B.J. Green, M. Marazzini, B. Hershey, A. Fardin, Q. Li, Z. Wang, G. Giangreco, F. Pisati, S. Marchesi, A. Disanza, E. Martini, S. Magni, G.V. Beznoussenko, C. Vernieri. R. Lobefaro, D. Parazzoli, P. Maiuri, K. Havas, M. Labib, S. Sigismund, P.P. Di Fiore, R.H. Gunby, S.O. Kelley, G. Scita.
Small, 2022, 2106097.

“nuPRISM: Microfluidic Genome-Wide Phenotypic Screening Platform for Cellular Nuclei.”

A. M. Abdrabou, B. T. V. Duong, K. Chen, R. S. Atwal, M. Labib, S. Lin, S. Angers and S. O. Kelley.
ACS Cent Sci, 2022, 8(12)1618-1626.

“Detection of SARS-CoV-2 Viral Particles using Direct, Reagent-Free Electrochemical Sensing.”

H. Yousefi, A. Mahmud, D. Chang, J. Das, S. Gomis, J.B. Chen, H. Wang, T. Been, L.Yip, E. Coomes, Z. Li, S. Mubareka, A. McGeer, N. Christie, S. Gray-Owen, A. Cochrane, J.M. Rini, E.H. Sargent, S.O. Kelley
Journal of the American Chemical Society, 2021, 143, 1722-1727. link

“Ultrasensitive Detection of Rare Leukemic B Cells in T Cell Populations.”

Z. Wang, E.H. Sargent, S.O. Kelley
Anal. Chem., 2021, 93, 2327-2335.

“AbCellera’s Success is Unprecedented: What Have We Learned?”

D. Sinton and S. O. Kelley
Lab Chip 2021,1(12)2330-2332

“Multication Perovskite 2D/3D Interfaces Form via Progressive Dimensional Reduction.”

A. H. Proppe, A. Johnston, S. Teale, A. Mahata, R. Quintero-Bermudez, E. H. Jung, L. Grater, T. Cui, T. Fileter, C.-Y. Kim, , S.O. Kelley, F. De Angelis, E. H. Sargent.
Nature Communications, 2021, 12, 1-9.

“Cell-Free DNA and Circulating Tumor Cell Kinetics in a Pre-Clinical Head and Neck Cancer Model Undergoing Radiation Therapy.”

N. Muhanna, D. Eu, H.H.L. Chan, C. Douglas, J.L. Townson, M.A. Di Grappa, R.M. Mohamadi, S.O. Kelley, S.V. Bratman, J. Irish
BMC Cancer, 2021, 143, 15606-15615.

“Phage-Based Profiling of Rare Single Cells Using Nanoparticle-Directed Capture”

Y. Ma, K. Chen, F. Xia, R. Atwal, H. Wang, S.U. Ahmed, L. Cardarelli, I. Lui, B. Duong, Z. Wang, J. A. Wells,  S.S. Sidhu, S.O. Kelley
ACS Nano, 2021, 15, 19202-19210.

“Bright and Stable Light-Emitting Diodes Based on Perovskite Quantum Dots in Perovskite Matrix.”

Y. Liu, Y. Dong, T. Zhu. D. Ma, A. Proppe, B. Chen, C. Zheng,  Y. Hou, S. Lee, B. Sun, E. H. Jung, F. Yuan, Y.-K. Wang, L.K. Sagar, S. Hoogland, F. P. Garcia de Arquer, M.-J. Choi, K. Singh, S.O. Kelley, O. Voznyy, Z.-H. Lu, E. H. Sargent.
Journal of the American Chemical Society, 2021, 143, 15606-15615.

“Tracking the Expression of Therapeutic Protein Targets in Rare Cells by Antibody-Mediated Nanoparticle Labelling and Magnetic Sorting.”

M. Labib, Z. Wang, S.U. Ahmed, R.M. Mohamadi, B. Duong, B. Green, E.H. Sargent
Nature Biomedical Engineering, 2021, 5, 41-52. link

“Circulating Tumor Cell Profiling for Precision Oncology.”

M. Labib, S.O. Kelley
Molecular Oncology, 2021, 15, 1622-1646.

“COVID-19: A Crisis Creating New Opportunities for Sensing.”

S.O. Kelley

ACS Sens, 2021, 6(4)1407.

“Cell-Free DNA and Circulating Tumor Cell Kinetics in a Pre-Clinical Head and Neck Cancer Model Undergoing Radiation Therapy.”

N. Muhanna, D. Eu, H.H.L. Chan, C. Douglas, J.L. Townson, M.A. Di Grappa, R.M. Mohamadi, S.O. Kelley, S.V. Bratman, J. Irish
BMC Cancer, 2021, 143, 15606-15615.

“Mitochondrial ATP Fuels ABC Transporter-mediated Drug Efflux in Cancer Chemoresistance.”

E. L. Giddings, E. P. Champagne, M.-H. Wu, J. M. Laffin, T. M. Thornton, F. Valenca-Pereira, R. Culp-Hill, K. A. Fortner, N. Romero, J. East, P. Cao, H. Arias-Pulido, K. S. Sidhu, B. Silverstrim. Y. Kam, S.O. Kelley, M. Pereira, S. E. Bates, J. Y. Bunn, S. N. Fiering, D. E. Matthews, R. W. Robey, D. Stich, A. D’Alessandro, M. Rincon.
Nature Communicaitons, 2021, 12, 1-19.

“Reagentless Biomolecular Analysis Using a Nanoscale Molecular Pendulum.”

J. Das, S. Gomis, J.B. Chen, H. Yousefi, S.Ahmed, A. Mahmud, W. Zhou, E. H. Sargent, S.O. Kelley
Nature Chemistry, 2021, 14, 428-434.

“A Microfluidic Platform Enables Comprehensive Gene Expression Profiling of Mouse Retinal Stem Cells.”

M. Labib, B. Coles, M. Poudineh, B. Innes, J. Belair-Hickey, S. Gomis, Z. Wang, G. Bader, E.H. Sargent, S.O. Kelley, D. van der Kooy
Lab on a Chip, 2021, in press.

“Strategies for Biomolecular Analysis and Continuous Physiological Monitoring.”

A. Clifford, J. Das, H. Yousefi, A. Mahmud, J.B. Chen, S.O. Kelley
Journal of the American Chemical Society, 2021, 143, 5281-5294. link

“Multifunctional 3D-Printed Wound Dressings.”

M. Alizadehgiashi, C.R. Nemr, M. Chekini, D. Pinto Ramos, N. Mittal, S.U. Ahmed, N. khuu, S.O. Kelley, E. Kumacheva
ACS Nano, 2021, 15, 12375-12387.

“Analyzing Proteins at the Single-Cell Level: The Challenge of the Proteome.”

M. Labib and S.O. Kelley
Nature Reviews Chemistry, 2020, 4, 143-158.

“Fluorescent Droplet Cytometry for On-Cell Phenotype Tracking.”

X. Yang, W. liu, D. C.-H. Chan, S.U. Ahmed, H. Wang, Z. Wang, C.R. Nemr, S.O. Kelley
Journal of the American Chemical Society, 2020, 142, 14805–14809.

“High-Performance Nucleic Acids Sensors for Liquid Biopsy Applications.”

J. Das and S.O. Kelley
Angew. Chem. Intl. Ed. 2020, 59, 2554-2564.

“Nanostructured Architectures Promote the Mesenchymal–Epithelial Transition for Invasive Cells.”

Z. Wang, F. Xia, M. Labib, M. Ahmadi, H. Chen, J. Das, S.U. Ahmed, S. Angers, E.H. Sargent, S.O. Kelley
ACS Nano, 2020, 14, 5324-5336.

“Magnetic Ranking Cytometry: Profiling Rare Cells at the Single-Cell Level.”

M. Labib, D.N. Philpott, Z. Wang, C. Nemr, J.B. Chen, E.H. Sargent, S.O. Kelley
Accounts of Chemical Research, 2020, 53, 1445-1457.

“A Multiplexed, Electrochemical Interface for Gene Circuit-Based Sensors.”

P. Sadat Mousavi, S.J. Smith, J.B. Chen, M. Karlikow, A. Tinafar, W. Liu, D. Ma, A.A. Green, S.O. Kelley,* K. Pardee*
Nature Chemistry, 2020, 12, 48-55.

“A New Era in Liquid Biopsy: From Genotype to Phenotype.”

S.O. Kelley, K. Pantel

Clinical Chemistry, 2020, 66, 89-96.

“Ultrasensitive and Rapid Quantification of Rare Tumorigenic Stem Cells in hPSC-Derived Cardiomyocyte Populations.” Z, Wang, M. Gagliardi, R.M. Mohamadi, S.U.

Ahmed, M. Labib, L. Zhang, Y. Zhou, E.H. Sargent, G.M. Keller
Science Advances, 2020, 6, eaay7629.

“Regioselective Magnetization in Semiconducting Nanorods.”

T.-T. Zhuang, Y. Li, X. Gao, M. Wei, F. P. García de Arquer, P. Todorović, J. Tian, G. Li, C. Zhang, X. Li, L. Dong, Y. Song, Y. Lu, X. Yang, L. Zhang, F. Fan, S.O. Kelley, S.-H. Yu, Z. Tang, E.H. Sargent
Nature Nanotechnology, 2020, 15, 192-197.

“Efficient Electrically Powered CO2 to Ethanol Via Suppression of Deoxygenation”

X. Wang, Z. Wang, F.P. García de Arquer, C.-T. Dinh, A. Ozden, Y.C. Li, D.-H. Nam, J. Li, Y.-S. Liu, J. Wicks, Z. Chen, M. Chi, B.Chen, Y.Wang, J. Tam, J.Y. Howe, A. Proppe, P. Todorović, F. Li, T.-T. Zhuang, C.M. Gabardo, A.R. Kirmani, C. McCallum, S.-F. Hung, Y. Lum, M. Luo, Y. Min, A. Xu, C.P. O’Brien, B. Stephen, B. Sun, A.H. Ip, L.J. Richter, S.O. Kelley, D. Sinton, E.H. Sargent.
Nature Energy, 2020, 5, 478-486.

“Multi-cation Perovskites Prevent Carrier Reflection from Grain Surfaces”

M.I. Saidaminov, K. Williams, M. Wei, A. Johnston, R. Quintero-Bermudez, M. Vafaie, J.M. Pina, A.H. Proppe, Y. Hou, G. Walters, S.O. Kelley, W.A. Tisdale, E.H. Sargent.
Nature Materials, 2020, 19, 412-418.

“Efficient Near-infrared Light-emitting Diodes based on Quantum Dots in Layered Perovskite”

L. Gao, L.N. Quan, F.P. García de Arquer, Y. Zhao, R. Munir, A. Proppe, R. Quintero-Bermudez, C. Zou, Z. Yang, M.I. Saidaminov, O. Voznyy, S. Kinge, Z. Lu, .O. Kelley, A. Amassian, J. Tang, E.H. Sargent.
Nature Photonics, 2020, 14, 227-233.

“Catalyst Synthesis Under CO2 Electroreduction Favours Faceting and Promotes Renewable Fuels Electrosynthesis”

Y. Wang, Z. Wang, C.-T. Dinh, A. Li, J.,Ozden, M. Golam Kibria, A. Seifitokaldani, C.-S. Tan, C.M. Gabardo, M. Luo, H. Zhou, F. Li, Y. Lum, C. McCallum, Y. Xu, M. Liu, A. Proppe, A. Johnston, P. Todorovic, T.-T. Zhuang, D. Sinton, S.O. Kelley, E.H. Sargent.
Nature Catalysis, 2020, 3, 98-106.

“Bioinspiration in Light Harvesting and Catalysis”

A.H. Proppe, Y.C. Li, A. Aspuru-Guzik, C.P. Berlinguette, C.J. Chang, R. Cogdell, A.G. Doyle, J. Flick, N.M. Gabor, R. van Grondelle, S. Hammes-Schiffer, S.A. Jaffer, S.O. Kelley, M. Leclerc, K. Leo, T.E. Mallouk, P. Narang, G.S. Schlau-Cohen, G.D. Scholes, A. Vojvodic, J.Y. Yang, E.H. Sargent.
Nature Reviews Materials, 2020, 5, 828-846.

“High-Throughput Genome-Wide Phenotypic Screening via Immunomagnetic Cell Sorting.”

B. Mair, P.M. Aldridge, R.S. Atwal, D. Philpott, M. Zhang, S.N. Masud, M. Labib, A.H.Y. Tong, E.H. Sargent, S. Angers, J. Moffat,* S.O. Kelley*
Nature Biomed. Eng. 2019, 3, 796-805.

“Peptide-Functionalized Nanostructured Microarchitectures Enable Rapid Mechanotransductive Differentiation.”

Z. Wang, L. Zhang, M. Labib, H. Chen, M. Wei, M. Poudineh, B.J. Green, B. Duong, J. Das, S. Ahmed, E.H. Sargent, S.O. Kelley,
ACS Applied Materials and Interfaces 2019, 11, 41030-41037.

“Potential-Responsive Surfaces for Dynamic Manipulation of Cell Adhesion, Release and Differentiation.”

L. Zhang, Z. Wang, J. Das, M. Labib, S. Ahmed, E.H. Sargent, S.O. Kelley,
Angew. Chem. Intl. Ed. 2019, 58, 14519-14523.

“Peptide-Mediated Electrochemical Steric Hindrance Assay for One-Step Detection of HIV Antibodies.”

S.S. Mahshid, S. Mahshid, A. Vallée-Bélisle, S.O. Kelley.
Anal. Chem. 2019, 91, 4943-4947.

“Nanoparticle-Mediated Capture and Electrochemical Detection of Methicillin-Resistant Staphylococcus aureus.”

C.R. Nemr, S.J. Smith, W. Liu, A.H. Mepham, R.M. Mohamadi, M. Labib, S.O. Kelley.
Anal. Chem. 2019, 91, 2847-2853.

“Nanostructure Architectures for Bimolecular Detection Inside and Outside of the Cell.”

J.B. Chen, H. Yousefi, C.R. Nemr, S. Gomis, R. Atwal, E.H. Sargent, S.O. Kelley.
Advanced Functional Materials, 2019, 1907701.

“Phenotypic Profiling of Circulating Tumor Cells in Metastatic Prostate Cancer Patients Using Nanoparticle-Mediated Ranking.” B.J. Green, V. Nguyen, E. Atenafu, P.

Weeber, B.T.V. Duong, P. Thiagalingam, M. Labib, R.M. Mohamadi, A.R. Hansen, A.M. Joshua, S.O. Kelley.
Anal. Chem. 2019, 91, 9348-9355.

“Lattice Anchoring Stabilizes Solution-Processed Semiconductors.”

M. Liu, Y. Chen, C.S. Tan, R. Quintero-Bermudez, A.H. Proppe, R. Munir, H. Tan, O. Voznyy, B. Scheffel, G. Walters, A.P.T. Kam, B. Sun, M.J. Choi, S. Hoogland, A. Amassian, S.O. Kelley, F.P. García de Arquer, E.H. Sargent.
Nature 2019, 570, 96-101.

“Anchored Ligands Facilitate Efficient B-Site Doping in Metal Halide Perovskites.”

Z. Yang, M. Wei, O. Voznyy, P. Todorovic, M. Liu, R. Quintero-Bermudez, P. Chen, J.Z. Fan, A.H. Proppe, L.N. Quan, G. Walters, H. Tan, J.W. Chang, U.S. Jeng, S.O. Kelley, E.H. Sargent.
J. Am. Chem. Soc. 2019, 141, 8296-8305.

“Contactless Measurements of Photocarrier Transport Properties in Perovskite Single Crystals.”

X. Gong, Z. Huang, R. Sabatini, C.S. Tan, G. Bappi, G. Walters, A. Proppe, M.I. Saidaminov, O. Voznyy, S.O. Kelley, E.H. Sargent.
Nature Commun. 2019, 10, 1591.

“Spectrally Resolved Ultrafast Exciton Transfer in Mixed Perovskite Quantum Wells.”

A.H. Proppe, M.H. Elkins, O. Voznyy, R.D. Pensack, F. Zapata, L.V. Besteiro, L.N. Quan, R. Quintero-Bermudez, P. Todorovic, S.O. Kelley, A.O. Govorov, S.K. Gray, I. Infante, E.H. Sargent, G.D. Scholes.
J. Phys. Chem. Lett. 2019, 10, 419-426.

“Combining Desmopressin and Docetaxel for the Treatment of Castration-Resistant Prostate Cancer in an Orthotopic Model.”

R. Bass, D. Roberto, D.Z. Wang, F.P. Cantu, R.M. Mohamadi, S.O. Kelley, L. Klotz, V. Venkateswaran.
Anticancer Res. 2019, 39, 113-118.

“Photochemically Cross-Linked Quantum Well Ligands for 2D/3D Perovskite Photovoltaics with Improved Photovoltage and Stability”

A. H. Proppe, M. Wei, B. Chen, R. Quintero-Bermudez, S. O. Kelley, E. H. Sargent.
J. Am. Chem. Soc. 2019, 141, 14180-14189.

“Single Cell mRNA Cytometry via Sequence-Specific Nanoparticle Clustering and Trapping.”

M. Labib, R.M. Mohamadi, M. Poudineh, S.U. Ahmed, I. Ivanov, C.L. Huang, M. Moosavi, E.H. Sargent, S.O. Kelley.
Nature Chemistry, 2018, 10, 489-495.

“Prismatic Deflection of Live Tumor Cells and Cell Clusters.”

P.M. Aldridge, M. Mukhopadhyay, S.U. Ahmed, W. Zhou, E. Christinck, R. Makonnen, E.H. Sargent, S.O. Kelley.
ACS Nano. 2018, 12, 12692-12700.

“Three-Dimensional Nanostructured Architectures Enable Efficient Neural Differentiation of Mesenchymal Stem Cells via Mechanotransduction.”

M. Poudineh, Z. Wang, M. Labib, M. Ahmadi, L. Zhang, J. Das, S. Ahmed, S. Angers, S.O. Kelley.
Nano Lett. 2018.18,7188-7193.

“Single-Cell Tumbling Enables High-Resolution Size Profiling of Retinal Stem Cells.”

S. Gomis, M. Labib, B.L.K. Coles, D. van der Kooy, E.H. Sargent, S.O. Kelley.
ACS Appl Mater Interfaces. 2018, 10, 34811-24816.

“Programmable Metal/Semiconductor Nanostructures for mRNA-Modulated Molecular Delivery.”

L. Zhang, S.R. Jean, X. Li, T. Sack, Z. Wang, S. Ahmed, G. Chan, J. Das, A. Zaragoza, E.H. Sargent, S.O. Kelley.
Nano Lett. 2018,18, 6222-6228.

“Curvature-Mediated Surface Accessibility Enables Ultrasensitive Electrochemical Human Methyltransferase Analysis.”

G. Wang, J. Das, S. Ahmed, C.R. Nemr, L. Zhang, M. Poudineh, E.H. Sargent, S.O. Kelley.
ACS Sens. 2018, 3, 1765-1772.

“Profiling Circulating Tumour Cells and Other Biomarkers of Invasive Cancers.”

M. Poudineh, E.H. Sargent, K. Pantel, S.O. Kelley
Nature Biomedical Engineering, 2018, 2, 74-82.

“Dynamic CTC Phenotypes in Metastatic Prostate Cancer Models Visualized Using Magnetic Ranking Cytometry.”

L. Kermanshah, M. Poudineh, S. Ahmed, L.N.M. Nguyen, S. Srikant, R. Makonnen, F.P. Cantu, M. Corrigan, S.O. Kelley
Lab on a Chip 2018, 18, 2055-2064.

“A Multifunctional Chemical Probe for Local Micropolarity and Microviscosity in Mitochondria.”

A. Jiménez-Sánchez, E. Lei, S.O. Kelley
Angew. Chem. Intl. Ed. Engl. 2018, 57, 8891-8895

“Combinatorial Probes for High-Throughput Electrochemical Analysis of Circulating Nucleic Acids.”

J. Das, I. Ivanov, T.S. Safaei, S.O. Kelley
Angew. Chem. Intl. Ed. Engl. 2018, 57, 3711-3716.

“A Fully-Integrated and Automated Testing Device for PCR-free Viral Nucleic Acid Detection in Whole Blood.”

W. Liu, J. Das, A.H. Mepham, C.R. Nemr, E.H. Sargent, S.O. Kelley
Lab on a Chip, 2018, 18, 1928-1935.

“DNA Polymerase Theta Increases Mutation Rates in Mitochondrial DNA.”

S. Wisnovsky, T. Sack, D. J. Pagliarini, R.R. Laposa, S.O. Kelley
ACS Chemical Biology 2018, 13, 900-908.

“Pore Shape Defines Paths of Metastatic Cell Migration.”

B.J. Green, M. Panagiotakoloulou, F. M. Pramotton, G. Stefopoulos, S. O. Kelley, D. Poulikakos, A. Ferrari
Nano Letters 2018, 18, 2140-2147.

“Mitochondrial Tyrosyl-DNA Phosphodiesterase 2 and its TDP2S Short Isoform.”

S.-Y. N. Huang, I. Dalla Rosa, S.A, Michaels, D.V. Tulumello, K. Agama, S. Khiati, S.R. Jean, S.A. Baechler, V.M. Factor, S. Varma, J. Murai, L.M.M. Jenkins, S.O. Kelley, Y. Pommier
EMBO Reports 2018, 19, e42139

“Picosecond Charge Transfer and Long Carrier Diffusion Lengths in Colloidal Quantum Dot Solids.”

A.H. Proppe, J. Xu, R.P. Sabatini, J.Z. Fan, B. Sun, S. Hoogland, S.O. Kelley, O. Voznyy, E.H. Sargent
Nano Lett. 2018,18, 7052-7059.

“Multibandgap quantum dot ensembles for solar-matched infrared energy harvesting.”

B. Sun, O. Ouellette, F.P. García de Arquer, O. Voznyy, Y. Kim, M. Wei, A.H. Proppe, M.I. Saidaminov, J. Xu, M. Liu, P. Li, J.Z. Fan, J.W. Jo, H. Tan, F. Tan, S. Hoogland, Z.H. Lu, S.O. Kelley, E.H. Sargent.
Nature Commun. 2018, 9, 4003.

“Compositional and orientational control in metal halide perovskites of reduced dimensionality.”

Quintero-Bermudez R, Gold-Parker A, Proppe AH, Munir R, Yang Z, Kelley SO, Amassian A, Toney MF, Sargent EH.
Nature Mater. 2018,10, 900-907.

“Metal-Organic Framework Thin Films on High-Curvature Nanostructures Toward Tandem Electrocatalysis.”

De Luna P, Liang W, Mallick A, Shekhah O, García de Arquer FP, Proppe AH, Todorović P, Kelley SO, Sargent EH, Eddaoudi M.
ACS Appl Mater Interfaces. 2018,10, 31225-31232.

“Metal-Organic Frameworks Mediate Cu Coordination for Selective CO2 Electroreduction.”

Nam DH, Bushuyev OS, Li J, De Luna P, Seifitokaldani A, Dinh CT, García de Arquer FP, Wang Y, Liang Z, Proppe AH, Tan CS, Todorović P, Shekhah O, Gabardo CM, Jo JW, Choi J, Choi MJ, Baek SW, Kim J, Sinton D, Kelley SO, Eddaoudi M, Sargent EH.
J. Am. Chem. Soc. 2018, 140, 11378-11386.

“2D Metal Oxyhalide-Derived Catalysts for Efficient CO2 Electroreduction.”

García de Arquer FP, Bushuyev OS, De Luna P, Dinh CT, Seifitokaldani A, Saidaminov MI, Tan CS, Quan LN, Proppe A, Kibria MG, Kelley SO, Sinton D, Sargent EH.
Adv Mater. 2018, 30, e1802858.

“Activated Electron-Transport Layers for Infrared Quantum Dot Optoelectronics.”

J. Choi, J.W. Jo, F.P.G. de Arquer, Y.B. Zhao, B. Sun, J. Kim, M.J. Choi, S.W. Baek, A.H. Proppe, A. Seifitokaldani, D.H. Nam, P. Li, O. Ouellette, Y. Kim, O. Voznyy, S. Hoogland, S.O. Kelley, Z.H. Lu, E. H. Sargent
Advanced Materials 2018, 30, 1801720.

“2D Matrix Engineering for Homogeneous Quantum Dot Coupling in Photovoltaic Solids.”

J. Xu, O. Voznyy, M. Liu, A.R. Kirmani, G. Walters, R. Munir, M. Abdelsamie, A.H. Proppe, A. Sarkar, F.P. García de Arquer, M. Wei, B. Sun, M. Liu, O. Ouellette, R. Quintero-Bermudez, J. Li, J. Fan, L. Quan, P. Todorovic, H. Tan, S. Hoogland, S.O. Kelley, M. Stefik, A. Amassian, E.H. Sargent.
Nature Nanotechnology. 2018, 13, 456-462.

“Hydronium-Induced Switching between CO2 Electroreduction Pathways.”

A. Seifitokaldani, C.M. Gabardo, T. Burdyny, C.T. Dinh, J.P. Edwards, M.G. Kibria, O.S. Bushuyev, S.O. Kelley, D. Sinton, E.H. Sargent
J. Am. Chem. Soc. 2018, 140, 3833-3837.

“Synthetic Control over Quantum Well Width Distribution and Carrier Migration in Low-Dimensional Perovskite Photovoltaics.”

A.H. Proppe, R. Quintero-Bermudez, H. Tan, O. Voznyy, S.O. Kelley, E.H. Sargent
J. Am. Chem. Soc. 2018, 140, 2890-2896.

“Electron-Phonon Interaction in Efficient Perovskite Blue Emitters.”

X. Gong, O. Voznyy, A. Jain, W. Liu, R. Sabatini, Z. Piontkowski, G. Walters, G. Bappi, S. Nokhrin, O. Bushuyev, M. Yuan, R. Comin, D. McCamant, S.O. Kelley, E. H. Sargent
Nature Materials. 2018, 17, 550-556.

“Catalyst Electro-redeposition Controls Morphology and Oxidation State for Selective Carbon Dioxide Reduction.”

P. De Luna, R. Quintero-Bermudez, C. T. Dinh, M. B. Ross, O. S. Bushuyev, P. Todorovic, T. Regier, S. O. Kelley, P. Yang, E. H. Sargent
Nature Catalysis, 2018, 1, 103-110.

“Tracking the Dynamics of Circulating Tumor Cell Phenotypes Using Nanoparticle-Mediated Magnetic Ranking.”

M. Poudineh, P.M. Aldridge, S. Ahmed, B.J. Green, L. Kermanshah, V. Nguyen, C. Tu, R.M. Mohamadi, R.K. Nam, A. Hansen, S.S. Sridhar, A. Finelli, N.E. Fleshner, A.M. Joshua, E.H. Sargent, S.O. Kelley
Nature Nanotechnology, 2017, 12, 274-282.

“Multifunctional Quantum Dot DNA Hydrogels.”

L. Zhang, S.R. Jean, S. Ahmed, P.M. Aldridge, X. Li, F. Fan, E.H. Sargent, S.O. Kelley
Nature Communications, 2017, doi:10.1038/s41467-017-00298-w.

“Bioassays: Universal Sensitivity Booster.”

S.O. Kelley,
Nature Biomedical Engineering, 2017, 1, 88.

“Delivery and Release of Small-Molecule Probes in Mitochondria Using Traceless Linkers.”

E.K. Lei and S.O. Kelley,
Journal of the American Chemical Society, 2017, 139, 9455-9458.

“Amplified Micromagnetic Field Gradients Enable High-Resolution Profiling of Rare Cell Subpopulations”

M. Poudineh, E.H. Sargent, and S.O. Kelley
ACS Appl. Mater. Interfaces, 2017, 9, 25683−2569.

“Power-Free, Digital and Programmable Dispensing of Picoliter Droplets using a Digit Chip”

A. Mepham, J. Besant, A. Weinstein, I. Burgess, E.H. Sargent, S.O. Kelley
Lab On A Chip, 2017, 17, 1505-1514.

“Biexciton Resonances Reveal Exciton Localization in Stacked Perovskite Quantum Wells.”

M.H. Elkins, R. Pensack, A.H. Proppe, O. Voznyy, L.N. Quan, S.O. Kelley, E.H. Sargent, G.D. Scholes
Journal of Physical Chemistry Letters, 2017, 8, 3895-3901.

“Chemistry-Driven Approaches to Ultrasensitive Nucleic Acid Detection.”

S.J. Smith, C.R. Nemr, S.O. Kelley
Journal of the American Chemical Society, 2017, 139, 1020-1028.

“Advancing Ultrasensitive Molecular and Cellular Analysis Methods to Speed and Simplify the Diagnosis of Disease.”

S.O. Kelley
Accounts of Chemical Research, 2017, 50, 503-507 (“Holy Grails in Chemistry” issue).

“Enhancing the Potency of Nalidixic Acid toward a Bacterial DNA Gyrase with Conjugated Peptides.”

M. Ahmed & S.O. Kelley,
ACS Chemical Biology, 2017, 12, 2563-2569.

“Profiling Functional and Biochemical Phenotypes of Circulating Tumor Cells Using a Two-Dimensional Sorting Device.”

M. Poudineh, M. Labib, S. Ahmed, L.N.M. Nguyen, L. Kermanshah, R.M. Mohamadi, E.H. Sargent, S.O. Kelley
Angew. Chem. Intl. Ed., 2017, 56, 163-168.

“What are Clinically-Relevant Levels of Cellular and Biomolecular Analytes?”

S.O. Kelley
ACS Sensors, 2017, 2, 193-197.

“Isolation of Phenotypically-Distinct Cancer Cells using Nanoparticle-Mediated Sorting.”

B.J. Green, L. Kermanshah, M. Labib, S.U. Ahmed, P.N. Silva, L. Mahmoudian, I.-H. Chang, R.M. Mohamadi, J.V. Rocheleau, S.O. Kelley,
ACS Applied Materials and Interfaces, 2017, 9, 20435-20443.

“Biomolecular Steric Hindrance Effects Are Enhanced on Nanostructured Microelectrodes.”

S.S. Mahshid, A. Vallee-Belisle, S.O. Kelley,
Analytical Chemistry, 2017, 89, 9751-9757.

“Steric Hindrance Assay for Secreted Factors in Stem Cell Culture.”

W. Zhou, S.S. Mahshid, W. Wang, A. Vallee-Belisle, P.W. Zandstra, E.H. Sargent, S.O. Kelley,
ACS Sensors, 2017, 2, 495-500.

“New Technologies for Rapid Bacterial Identification and Antibiotic Resistance Profiling.”

S.O. Kelley
SLAS Technology, 2017, 22, 113-121.

“High-Curvature Nanostructuring Enhances Probe Display for Biomolecular Detection.”

P. De Luna, S.S. Mahshid, J. Das, B. Luan, E.H. Sargent, S.O. Kelley, R. Zhou
Nano Letters, 2017, 17, 1289-1295.

“Electrochemical DNA-Based Immunoassay That Employs Steric Hindrance to Detect Small Molecules Directly in Whole Blood.”

S.S. Mahshid, F. Ricci, S.O. Kelley, A. Vallee-Belisle,
ACS Sensors, 2017, 2, 718-723.

“Broadband Epsilon-near-Zero Reflectors Enhance the Quantum Efficiency of Thin Solar Cells at Visible and Infrared Wavelengths.” A.J. Labelle, M.

Bonifazi, Y. Tian, C. Wong, S. Hoogland, G. Favraud, G. Walters, B. Sutherland, M. Liu, J. Li, X. Zhang, S.O. Kelley, E.H. Sargent, A. Fratalocchi,
ACS Applied Materials and Interfaces, 2017, 9, 5556-5565.

“Mixed Quantum Dot Solar Cells.”

Z. Yang, J. Z Fan, A.H. Proppe, F. P. García de Arquer, D. Rossouw, O. Voznyy, X. Lan, M. Liu, G. Walters, R. Quintero-Bermudez, B. Sun, S. Hoogland, S.O. Kelley, E. H. Sargent
Nature Communications, 2017, DOI: 10.1038/s41467-017-01362-1.

“Mitochondrial DNA Repair and Replication Proteins Revealed by Targeted Chemical Probes.”

S. Wisnovsky, S.R. Jean, S.O. Kelley
Nature Chemical Biology, 2016, 12, 567-573.

“DNA Clutch Probes for Circulating Tumor DNA Analysis.”

J. Das, I. Ivanov, E.H. Sargent, S.O. Kelley
Journal of the American Chemical Society, 2016, 138, 11009-11016.

“Mechanistic Control of the Growth of Three-Dimensional Gold Sensors.”

S. Mahshid, A.H. Mepham, S.S. Mahshid, I.B. Burgess, T.S.Safaei, E.H. Sargent, S.O. Kelley
Journal of Physical Chemistry C, 2016, 120, 21123-21132.

“Interrogating Circulating Microsomes and Exosomes Using Metal Nanoparticles.”

Y.-G. Zhou, R.M. Mohamadi, M. Poudineh, L. Kermanshah, S. Ahmed, T.S. Safaei, R.K. Nam, E.H. Sargent, S.O. Kelley
Small, 2016, 12, 727-732.

“Beyond CTC Capture: Next-Generation Devices and Materials.”

B. Green, T. Saberi Safaei, A. Mepham, M. Labib, R.M. Mohamadi, S.O. Kelley
Angew. Chem. Intl. Ed., 2016, 55, 1252-1265.

“Mitochondrial Chemical Biology: New Probes Elucidate the Secrets of the Powerhouse of the Cell.”

S. Wisnovsky, E.K. Lei, S.R. Jean, S.O. Kelley
Cell Chemical Biology, 2016, 23, 917-927.

“Image-Reversal Soft Lithography: Fabrication of Ultrasensitive Biomolecular Detectors.”

T.S.S. Safaei, J. Das, S.S. Mahshid, P.M. Aldridge, E.H. Sargent, S.O. Kelley
Advanced Healthcare Materials, 2016, 5, 893-899.

“Electrochemical Methods for the Analysis of Clinically-Relevant Biomolecules.”

M. Labib, E.H. Sargent, S.O. Kelley
Chemical Reviews, 2016, 116, 9001-9090.

“Aptamer and Antisense-Mediated Two-Dimensional Isolation of Specific Cancer Cell Subpopulations.”

M. Labib, B. Green, R. Mohamadi, A. Mepham, S. Ahmed, L. Mahmoudian, I.-H. Chang, E.H. Sargent, S.O. Kelley
Journal of the American Chemical Society, 2016, 138, 2476-2479.

“Enhanced Electrocatalytic Carbon Dioxide Reduction via Field-Inducted Reagent Concentration.”

M. Liu, Y. Pang, B. Zhang, P. De Luna, O. Voznyy, J. Xu, X. Zheng, C. T. Dinh, F. Fan, C. Cao, F. P. García de Arquer, T. S. Safaei, A. Mepham, A. Klinkova, E. Kumacheva, T. Filleter, D. Sinton, S.O. Kelley and E. H. Sargent
Nature, 2016, 537, 382-386.

“High-Density Nanosharp Microstructures Enable Efficient Carbon Dioxide Electroreduction.”

T.S. Safaei, A. Mepham, X. Zheng, Y. Pang, C.-T. Dinh, D. Sinton, S.O. Kelley, E.H. Sargent,
Nano Letters, 2016, 11, 7224-7228.

“Mitochondria-Targeted Doxorubicin: a New Therapeutic Strategy Against Doxorubicin-Resistant Osteosarcoma.”

I. Buondonno, E. Gazzano, S.R. Jean, V. Audrito, J. Kopecka, M. Fanelli, I. C. Salaroglio, C. Costamagna, I. Roato, E. Mungo, C. M. Hattinger, S. Deaglio, S.O. Kelley, M. Serra, C. Riganti,
Molecular Cancer Therapeutics, 2016, 15, 2640-2652.

“Peptide-Mediated Delivery of Chemical Probes and Therapeutics to Mitochondria.”

S.R. Jean, M. Ahmed, E.K. Lai, S.P. Wisnovsky
Accounts of Chemical Research, 2016, 49, 1893-1902.

“An Electrochemical Clamp Assay for Direct, Rapid Analysis of Circulating Nucleic Acids in Serum.”

J. Das, I. Ivanov, E.H. Sargent, S.O. Kelley
Nature Chemistry, 2015, 7, 569-575.

“Peptide Targeting of an Antibiotic Prodrug Towards Phagosome-Entrapped Mycobacteria.”

M.P. Pereira, J. Shi, S.O. Kelley
ACS Infectious Disease, 2015, 1, 586-592.

“Mitochondrial Targeting of Doxorubicin Eliminates Nuclear Effects Associated with Cardiotoxicity.”

S.R. Jean, D.V. Tulumello, C. Riganti, S.U. Liyanage, A.D. Schimmer, S.O. Kelley
ACS Chemical Biology, 2015, 10, 2007-2015.

“Disease Detectors.”

S.O. Kelley
Scientific American, 2015, 313, 49-51.

“Fractal Circuit Sensors Enable Rapid Quantification of Biomarkers for Donor Lung Assessment for Transplantation.”

A.T. Sage, J.D. Besant, L. Mahmoudian, M. Poudineh, X. Bai, R. Zamel, M. Hsin, E.H. Sargent, M. Cypel, M. Liu, S. Keshavjee, S.O. Kelley
Science Advances, 2015, 1, e1500417. (featured in C&E News)

“Using the Inherent Chemistry of the Endothelin-1 Peptide to Develop a Rapid Assay for Pre-transplant Donor Lung Assessment.”

A.T. Sage, X. Bai, M. Cypel, M. Liu, S. Keshavjee, S.O. Kelley
Analyst, 2015, 140, 8092-8096.

“Sorting of Circulating Tumor Cells by Epithelial Antigen Expression during Disease Progression in an Animal Model.”

N. Muhanna, A. Mepham, R. Mohamadi, H. Chan, T. Khan, M. Akens, J.D. Besant, J. Irish, S.O. Kelley
Nanomedicine: Nanotechnology, Biology, and Medicine, 2015, 11, 1613-1616.

“In Situ Electrochemical ELISA for Specific Identification of Captured Cancer Cells.”

T. Saberi Safaei, R.M. Mohamadi, E.H. Sargent, S.O. Kelley
ACS Appl. Mater. Interfaces, 2015, 7, 14165-14169. *Selected as an ACS Editors Choice Article

“Sample-to-Answer Isolation and mRNA Profiling of Circulating Tumor Cells.”

R. M. Mohamadi, I. Ivanov, J. Stojcic, R.K. Nam, E.H. Sargent, S.O. Kelley
Analytical Chemistry, 2015, 87, 6258–6264

“Rapid Electrochemical Phenotypic Profiling of Antibiotic-Resistant Bacteria.”

J.D. Besant, E.H. Sargent, S.O. Kelley
Lab on a Chip, 2015, 15, 2799-2807.

“Programmable Definition of Nanogap Electronic Devices with Self-Inhibited Reagent Depletion.”

B. Lam, W. Zhou, E.H. Sargent, S.O. Kelley
Nature Communications, 2015, 6, 6940.

“Ultrasensitive Visual Readout of Nucleic Acids using Electrocatalytic Fluid Displacement.”

J.D. Besant, J. Das, I.B. Burgess, W. Liu, E.H. Sargent, S.O. Kelley
Nature Communications, 2015, 6, 6978.

“Velocity Valleys Enable Efficient Capture and Spatial Sorting of Nanoparticle-Bound Cancer Cells.”

J.D. Besant, R.M. Mohamadi, P. Aldridge, Y.Li, E.H. Sargent, S.O. Kelley
Nanoscale, 2015, 7, 6278-6285.

“Nanoparticle-Mediated Binning and Profiling of Heterogeneous Circulating Tumor Cell Subpopulations.”

R.M. Mohamadi, I. Ivanov, J.D. Besant, A. Malvea, A. Mepham, A.L. Allan, L.E. Lowes, R.K. Nam, E.H. Sargent, S.O. Kelley
Angew. Chem. Intl. Ed., 2015, 127, 141-145. (featured in Science, “Editor’s Choice”).

“A Digital Microfluidic Device with Integrated Nanostructured Microelectrodes for Electrochemical Immunoassays.”

D.G. Rackus, M.D.M. Dryden, A. Zaragoza, J. Lamanna, B. Lam, S.O. Kelley, A.R. Wheeler
Lab on a Chip, 2015, 15, 3776-3784.

“Highly Specific Electrochemical Analysis of Cancer Cells using Multi-Nanoparticle Labeling.”

Y. Wan*, Y. Zhou*, M. Poudineh, T. Saberi Safaei, R.M. Mohamadi, E.H. Sargent, S.O. Kelley
Angew. Chem. Intl. Ed., 2014, 53, 13361-13365.

“Effect of Microelectrode Structure on Electrocatalysis at Nucleic Acid-Modified Sensors.”

Y. Zhou, Y. Wan, A. Sage, M. Poudineh, S.O. Kelley
Langmuir, 2014, 30, 14322-14328.

“Structural Modifications of Mitochondria-Targeted Chlorambucil Alter Cell Death Mechanism but Preserve MDR Evasion.”

S.R. Jean, M.P. Pereira, S.O. Kelley
ACS. Mol. Pharm., 2014, 8, 2675-2682.

“Ultrasensitive Electrochemical Biomolecular Detection using Nanostructured Microelectrodes.”

A.T. Sage, J.D. Besant, B. Lam, E.H. Sargent, S.O. Kelley,
Acc. Chem. Res., 2014, 47, 2417-2425

“Three-Dimensional, Sharp-Tipped Electrodes Concentrate Applied Fields to Enable Direct Electrical Release of Intact Biomarkers from Cells.”

M. Poudineh, R. Mohamedi, A. Sage, L. Mahmoudian, E.H. Sargent, S.O. Kelley
Lab on a Chip, 2014, 14, 1785-1790.

“Advancing the Speed, Sensitivity and Accuracy of Biomolecular Detection with Multi-Length Scale Engineering.”

S.O. Kelley, C.A. Mirkin, D.R. Walt, R.F. Ismagilov, M. Toner, E.H. Sargent,
Nature Nanotechnology, 2014, 9, 969-980.

“Cellular Uptake of Substrate-Initiated Cell-Penetrating Poly(disulfide)s.”

G. Giulio, E.-K. Bang, G. Molinard, D. Tulumello, S. Ward, S.O. Kelley, A. Roux, N. Sakai, S. Matile
J. Am. Chem. Soc., 2014, 136, 6069-6074.

“Molecular Vehicles for Mitochondrial Chemical Biology and Drug Delivery.”

S.R. Jean, D.V. Tulumello, S.P. Wisnovsky, E.K. Lei, M.P. Pereira
ACS Chem. Biol., 2014, 9, 323-333.

“Targeting Mitochondrial DNA with a Platinum-Based Anticancer Agent.”

S.P. Wisnovsky, J.J. Wilson, R. J. Radford, M.P. Pereira, M. Chan, R. Laposa, S.J. Lippard, S.O. Kelley
Chem. Biol., 2013, 20, 1323-1328.

“Proximal Bacterial Lysis and Detection in Nanoliter Wells Using Electrochemistry.”

J.D. Besant, J. Das, E.H. Sargent, S.O. Kelley
ACS Nano, 2013, 7, 8183-8189.

“Tuning the Intracellular Bacterial Targeting of Peptidic Vectors.”

E. Lei, M. P. Pereira, S.O. Kelley,
Angew. Chem. Intl. Ed., 2013, 52, 9660-9663.

“Solution-Based Circuits Enable Rapid and Multiplexed Pathogen Detection.”

B. Lam, R.D. Holmes, L. Live, A. Sage, E. H. Sargent, S.O. Kelley
Nature Comm., 2013, 4, 2001.

“Tuning the Bacterial Detection Sensitivity of Nanostructured Microelectrodes.”

J. Das, S.O. Kelley
Anal. Chem., 2013, 85, 7333-7338.

“Targeted Delivery of Doxorubicin to Mitochondria.”

G. Chamberlain, D.V Tulumello, S.O. Kelley
ACS Chem. Biol., 2013, 8, 1389-1395.

“An Electrochemical ELISA Featuring Proximal Reagent Generation: Detection of HIV Antibodies in Clinical Samples.”

A. Bhimji, A. Zaragoza, L. Live, S.O. Kelley
Anal. Chem., 2013, 85, 6813-6819.

“Optimized Templates for Bottom-Up Growth of High-Performance Integrated Biomolecular Detectors.”

B. Lam, R.D. Holmes, J. Das, M. Poudineh, A. Sage, E.H. Sargent, S.O. Kelley
Lab on a Chip, 2013, 13, 2569-2575.

“Re-directing an Alkylating Agent to Mitochondria Alters Drug Target and Cell Death Mechanism.”

R. Mourtada, S. B. Fonseca, S.P. Wisnovsky, M.P. Pereira, X. Wang, R. Hurren, J. Parfitt, L. Larsen, R.A.J. Smith, M.P. Murphy, A.D. Schimmer, S.O. Kelley
PLOS One, 2013, 8, e60253.

“Rapid and Specific Electrochemical Detection of Prostate Cancer Cells Using an Aperture Sensor Array.”

M. Moscovici, A. Bhimji, S.O. Kelley
Lab on a Chip, 2013, 13, 940-946.

“Chip-Based Nanostructured Sensors Enable Accurate Identification and Classification of Circulating Tumor Cells in Prostate Cancer Patient Blood Samples .”

I. Ivanov, J. Stojcic, A. Stanimirovic, E. Sargent, R.K. Nam, S.O. Kelley
Anal. Chem., 2013, 85, 398-403.

“DNA-Based Programming of Quantum Dot Properties.”

K.B. Cederquist, S.O. Kelley
WIREs: Nanomedicine and Nanobiotechnology, 2013, 5, 86-96.

“An Ultrasensitve, Universal Detector Based on Neutralizer Displacement.”

J. Das, K.B. Cederquist, P. Lee, E.H. Sargent, S.O. Kelley
Nature Chemistry, 2012, 4, 642-648.

“Polymerase Chain Reaction-Free, Sample-to-Answer Bacterial Detection in 30 Minutes with Integrated Cell Lysis.”

B. Lam, Z. Fang, E.H. Sargent, S.O. Kelley
Anal. Chem., 2012, 84, 21-25.

“Tuning the Activity of Mitochondria-Penetrating Peptides for Delivery or Disruption.”

K.L. Horton, M.P. Pereira, K.M. Stewart, S.B. Fonseca, S.O. Kelley
ChemBioChem, 2012, 13, 476-485.

“Nanostructured Biomolecular Detectors: Pushing Performance at the Nanoscale.”

K.B. Cederquist, S.O. Kelley
Curr. Opin. Chem. Biol., 2012, 16, 415.

“DNA-Based Programming of Quantum Dot Valency, Self-Assembly, and Luminescence”

G. Tikhomirov, S. Hoogland, P.E. Lee, A. Fischer, E.H. Sargent, S.O. Kelley
Nature Nanotechnology, 2011, 6, 485.

“Direct Genetic Analysis of Ten Cancer Cells: Tuning Molecular Probe Design for Efficient mRNA Capture”

E. Vasilyeva, Z. Fang, M. Minden, E.H. Sargent, S.O. Kelley
Angew. Chem. Intl. Ed., 2011, 50, 4137.

“Maximizing the Therapeutic Window of an Antimicrobial Drug by Imparting Mitochondrial Sequestration in Human Cells “

M.P. Pereira, S.O. Kelley
J. Am. Chem. Soc., 2011, 133, 3260.

“Hierarchical Nanotextured Microelectrodes Overcome the Molecular Transport Barrier to Achieve Rapid, Direct Bacterial Detection”

L. Soleymani, Z. Fang, B. Lam, X. Bin, E. Vasilyeva, A. Ross, E.H. Sargent, S.O. Kelley
ACS Nano, 2011, 5, 3360.

“Development of Novel Peptides for Mitochondrial Drug Delivery: Amino Acids Featuring Delocalized Lipophilic Cations”

K.M. Stewart, R. Mourtada, S.O. Kelley
Pharm. Res., 2011, 28, 2808.

“Peptide-Chlorambucil Conjugates Combat Pgp-Dependent Drug Efflux”

S.B. Fonseca, S.O. Kelley
ACS Med. Chem. Lett., 2011, 2, 419.

“Re-routing Chlorambucil to Mitochondria Enhances Potency and Combats Drug Resistance in Cancer Cells”

S.B. Fonseca, M.P. Pereira, R. Mourtada, M. Gronda, R. Hurren, M.D. Minden, A.D. Schimmer, S.O. Kelley
Chem. Biol., 2011, 18, 445.

“Protein Detection Using Arrayed Microsensor Chips: Tuning Sensor Footprint to Achieve Ultrasensitive Readout of CA-125 in Serum and Whole Blood.”

J.Das, S.O. Kelley
Analytical Chemistry, 2011, 83, 1167

“Solvatochromic Reagents for Multicomponent Reactions and their Utility in the Development of Cell-Permeable Macrocyclic Peptide Vectors”

B.H.Rotstein, R. Mourtada, S.O. Kelley, A.K. Yudin
Chemistry, 2011, 17, 12257.

“Nanostructuring of Sensors Determines the Hybridization of Biomolecular Capture.”

X. Bin, E.H. Sargent, S.O. Kelley
Analytical Chemistry, 2010, 82, 5928.

“Nucleic Acid-Passivated Nanocrystals: Biomolecular Templating of Form and Function.”

N. Ma, G. Tikhomirov, S.O. Kelley
Accounts of Chemical Research, 2010, 43, 173.

“The Antiparasitic Agent Ivermectin Induces Chloride-Dependent Membrane Hyperpolarization and Cell Death in Leukemia Cells.”

S. Sharmeen, M. Skrtic, M.A Sukhai, R. Hurren, M. Gronda, X. Wang, S.B. Fonseca, H. Sun, M.D. Minden. R. Batey, A. Datti, J. Wrana, S.O. Kelley, A.D. Schimmer
Blood, 2010, 116, 3593.

“Programming the Detection Limits of Biosensors through Controlled Nanostructuring.”

L. Soleymani, Z. Fang, E.H. Sargent, S.O. Kelley
Nature Nanotechnology, 2009, 4, 844.

“Direct Profiling of Cancer Biomarkers in Tumour Tissue Using a Multiplexed Nanostructured Microelectrode Integrated Circuit. “

Z. Fang, L. Soleymani, G. Pampalakis, M. Yoshimoto, J.A. Squire, E. H. Sargent, S.O. Kelley
ACS Nano, 2009, 3, 3207.

“Nanostructuring of Patterned Microelectrodes to Enhance the Sensitivity of Electrochemical Nucleic Acids Detection. “

L. Soleymani, X. Sun, H. Yang, B.J. Taft, E. H. Sargent, S.O. Kelley
Angew. Chem. Intl. Ed., 2009, 48, 8457.

“Recent Advances in the Biological and Medical Applications of Cell-Penetrating Peptides.”

S.B. Fonseca, M. Pereira, S.O. Kelley
Adv. Drug. Del. Rev., 2009, 61, 953.

“One-step Synthesis of DNA-Programmed Semiconductor Nanocrystals.”

N. Ma, E.H. Sargent, S.O. Kelley
Nature Nanotechnology, 2009, 4, 121.

“Direct Electrocatalytic mRNA Detection Using PNA-Nanowire Sensors.”

Z. Fang & S.O. Kelley
Anal. Chem., 2009, 81, 612.

“An Electrochemical Immunosensor Based on Antibody-Nanowire Conjugates.”

G. Pampalakis & S.O. Kelley
The Analyst, 2009, 134, 447

“Mitochondria-Penetrating Peptides: Sequence Effects and Model Cargo Transport.”

L. Yousif, K.M. Stewart, K.L. Horton, S.O. Kelley
ChemBioChem, 2009, 10, 2081.

“Engineered Apoptosis-Inducing Peptides with Enhanced Mitochondrial Localization and Potency.”

K.L. Horton, S.O. Kelley
J. Med. Chem., 2009, 52, 3293.

“Targeting Mitochondria with Organelle-Specific Compounds: Strategies and Applications.”

L. Yousif, K.M. Stewart, and S.O. Kelley
ChemBioChem, 2009, 10, 1939.

“Nanomaterials for Ultrasensitive Electrochemical Biosensing.”

H. Lord & S.O. Kelley
J. Matl. Chem., 2009, 19, 3127.

“A General Phase-Transfer Protocol for Metal Ions and its Application in Nanocrystal Synthesis. “

J. Yang, E.H. Sargent, S.O. Kelley, J. Ying
Nature Materials, 2009, 4, 844.

“Potential Use of Cetrimonium Bromide as an Apoptosis-Promoting Anticancer Agent for Head and Neck Cancer..”

E. Ito, K.W. Yip D. Katz, S.B. Fonseca, D.W. Hedley, S. Chow, G.W Xu, T.E. Wood, C. Bastianutto, A.D. Schimmer, S.O. Kelley, F.F. Liu
Molecular Pharmacology, 2009, 76, 969.

“Cell-Permeable Peptides as Delivery Vehicles for Biology and Medicine.”

K.M. Stewart, K.L. Horton, S.O. Kelley
Org. Biomol. Chem., 2008, 6, 2242.

“Mitochondria-Penetrating Peptides.”

K.L. Horton, K.M. Stewart, S.B. Fonseca, Q. Guo, S.O. Kelley
Chemistry & Biology, 2008, 15, 375.

“Biotemplated Nanostructures: Directed Assembly of Electronic and Optical Materials using NanoscaleComplementarity.”

N. Ma, E.H. Sargent, S.O.Kelley
J. Mat. Chem., 2008, 18, 954.

“Measurement Science: the Engine of Chemical Biology.”

S.O. Kelley, D.R. Walt
Curr. Opin. Chem. Biol., 2008, 12, 473.

“A Comparison of Quality of Dispersion of Single Wall Carbon Nanotubes using Different Surfactants and Biomolecules.”

R. Haggenmueller, s. Rahatekar, J. Fagen, J. Chun, M. Becker, T. Krauss, R. Naik, L. Carlson, J. Kadla, P. Trulove, D. Fox, Z. Fang, S.O. Kelley, J. Gilman*,
Langmuir, 2008, 24, 5070.